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IL7R 抗体

IL7R 适用: 人 FACS 宿主: 小鼠 Monoclonal A019D5 unconjugated
产品编号 ABIN2664190
发货至: 中国
  • 抗原 See all IL7R 抗体
    IL7R (Interleukin 7 Receptor (IL7R))
    适用
    • 110
    • 50
    • 26
    • 7
    • 4
    • 2
    • 1
    宿主
    • 81
    • 36
    • 28
    • 1
    • 1
    小鼠
    克隆类型
    • 81
    • 64
    • 2
    单克隆
    标记
    • 63
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    • 4
    • 4
    • 4
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    • 2
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    • 1
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    This IL7R antibody is un-conjugated
    应用范围
    • 85
    • 77
    • 45
    • 26
    • 26
    • 13
    • 13
    • 9
    • 8
    • 8
    • 5
    • 3
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    A019D5
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IL7R Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IL7R (Interleukin 7 Receptor (IL7R))
    别名
    CD127 (IL7R 产品)
    别名
    IL7R antibody, CD127 antibody, IL-7Ralpha antibody, CDW127 antibody, IL-7R-alpha antibody, IL7RA antibody, ILRA antibody, IL-7RA antibody, interleukin 7 receptor antibody, IL7R antibody, Il7r antibody
    背景
    CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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