IL7R 抗体 (AA 21-236)
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北京 101111
Quick Overview for IL7R 抗体 (AA 21-236) (ABIN6939786)
抗原
See all IL7R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 21-236
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原理
- CD127 / IL7R (Marker of T-Reg Cells) Antibody
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特异性
- The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID).
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 21-236) of human CD127 protein (IL7R) (exact sequence is proprietary)
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亚型
- IgG2c, kappa
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应用备注
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Positive Control: K562, HeLa, Daudi or Jurkat cells. Tonsil, Lymph Node or Spleen.
Known Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- IL7R (Interleukin 7 Receptor (IL7R))
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别名
- IL7R
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背景
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CD127, IL-7 receptor subunit alpha, IL-7R-alpha, IL7R, IL7RA, IL7R alpha, ILRA, Interleukin 7 receptor alpha chain, Interleukin 7 receptor
Daudi or Jurkat cells. Tonsil, HeLa, K562, lymph node or spleen.
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分子量
- 52-72kDa
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基因ID
- 3575, 591742, 635723
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UniProt
- P16871
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
抗原
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