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Caspase 1 抗体

CASP1 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 5B10 unconjugated
产品编号 ABIN2664091
发货至: 中国
  • 抗原 See all Caspase 1 (CASP1) 抗体
    Caspase 1 (CASP1)
    适用
    • 99
    • 35
    • 29
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 110
    • 10
    • 3
    • 1
    大鼠
    克隆类型
    • 102
    • 22
    单克隆
    标记
    • 82
    • 19
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Caspase 1 antibody is un-conjugated
    应用范围
    • 97
    • 52
    • 49
    • 21
    • 14
    • 14
    • 12
    • 5
    • 3
    • 3
    • 3
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    5B10
    亚型
    IgG2a
    Top Product
    Discover our top product CASP1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    Caspase 1 (CASP1)
    别名
    Caspase-1 (CASP1 产品)
    背景
    Caspase -1 plays a vital role in cleaving the inactive procytokine pro-IL-1 beta to generate the active 17 kd mature form of IL-1beta, a key mediator of inflammation. Active caspase-1 (ICE) is derived a single proenzyme of 45 Kd. An active ICE comprises two subunits of P20 and two subunits of P10 after removal a large amino-terminal pro-domain and a small linker peptide. Caspase-1 is reported to be involved in CD95- mediated apoptosis. Four alternatively spliced variants of caspase-1 have been reported, with mw ranging from 30-48 kd.
    途径
    Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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