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NOTCH3 抗体 (PE)

NOTCH3 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal MHN3-21 PE
产品编号 ABIN2663861
发货至: 中国
  • 抗原 See all NOTCH3 抗体
    NOTCH3 (Notch 3 (NOTCH3))
    适用
    • 50
    • 16
    • 11
    • 1
    宿主
    • 34
    • 16
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 38
    • 17
    单克隆
    标记
    • 30
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOTCH3 antibody is conjugated to PE
    应用范围
    • 27
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    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    MHN3-21
    亚型
    IgG1 kappa
    Top Product
    Discover our top product NOTCH3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    NOTCH3 (Notch 3 (NOTCH3))
    别名
    Notch 3 (NOTCH3 产品)
    别名
    CADASIL antibody, CASIL antibody, IMF2 antibody, AW229011 antibody, N3 antibody, hpbk antibody, fa14b08 antibody, notch5 antibody, wu:fa14b08 antibody, notch 3 antibody, NOTCH3 antibody, Notch3 antibody, notch3 antibody
    背景
    The Notch receptors are highly conserved from invertebrates to mammals. While Notch 1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors. Notch 3 has a number of structural and functional differences. The binding of Notch 3 to its ligands results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus. This translocation triggers a series of signaling processes. Notch 3 is primarily expressed in adult arterial smooth muscle cells. Notch3 gene mutation can cause CADASIL, a hereditary early stroke syndrome.
    途径
    Notch Signaling
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