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CLEC7A 抗体 (PE)

CLEC7A 适用: 小鼠 ICFC 宿主: 大鼠 Monoclonal RH1 PE
产品编号 ABIN2663426
发货至: 中国
  • 抗原 See all CLEC7A 抗体
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    适用
    • 55
    • 36
    • 6
    • 1
    小鼠
    宿主
    • 40
    • 17
    • 16
    大鼠
    克隆类型
    • 41
    • 27
    单克隆
    标记
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    • 1
    • 1
    • 1
    • 1
    • 1
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    This CLEC7A antibody is conjugated to PE
    应用范围
    • 42
    • 37
    • 23
    • 22
    • 9
    • 8
    • 7
    • 5
    • 3
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    • 1
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    Intracellular Flow Cytometry (ICFC)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    RH1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CLEC7A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    别名
    CD369 (CLEC7A 产品)
    别名
    CLEC7A antibody, BGR antibody, Clecsf12 antibody, beta-GR antibody, CANDF4 antibody, CLECSF12 antibody, DECTIN1 antibody, Clec7b antibody, RGD1565140 antibody, C-type lectin domain containing 7A antibody, C-type lectin domain family 7, member a antibody, CLEC7A antibody, Clec7a antibody
    背景
    CD369 (Dectin-1), also known as CLEC7A, is a 43 kD type II transmembrane protein. The extracellular portion of Dectin-1 contains one C-type lectin domain, and its cytoplasmic tail has one immunoreceptor tyrosine-based activation motif (ITAM). Dectin-1 binds β-1,3-linked and β-1,6-glucans (abundant in the cell wall of fungi and yeast), mediates phagocytosis, and induces cytokine production and oxidative burst. It is also involved in TLR2-mediated NF-kB activation. Dectin-1 is expressed by macrophages, neutrophils, dendritic, and Langerhans cells.
    途径
    Activation of Innate immune Response
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