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HVEM 抗体 (PE)

TNFRSF14 适用: 小鼠 FACS 宿主: Armenian Hamster Monoclonal HMHV-1B18 PE
产品编号 ABIN2663260
发货至: 中国
  • 抗原 See all HVEM (TNFRSF14) 抗体
    HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))
    适用
    • 65
    • 7
    • 1
    • 1
    小鼠
    宿主
    • 53
    • 15
    • 1
    • 1
    • 1
    Armenian Hamster
    克隆类型
    • 53
    • 16
    • 2
    单克隆
    标记
    • 37
    • 8
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HVEM antibody is conjugated to PE
    应用范围
    • 44
    • 35
    • 24
    • 22
    • 13
    • 13
    • 9
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    HMHV-1B18
    亚型
    IgG
    Top Product
    Discover our top product TNFRSF14 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))
    别名
    CD270 (TNFRSF14 产品)
    别名
    ATAR antibody, CD270 antibody, HVEA antibody, HVEM antibody, LIGHTR antibody, TR2 antibody, Atar antibody, HveA antibody, Hvem antibody, Tnfrs14 antibody, TNF receptor superfamily member 14 antibody, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) antibody, Tnfrsf14 antibody, TNFRSF14 antibody
    物质类
    Viral Protein
    背景
    Herpes Virus Entry Mediator (HVEM, TR2) is a type I transmembrane protein of TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HAS) entry. Binding of HSV viral envelope glycoprotein D to this receptor has been shown to be part of the viral entry mechanism. It is expressed on most cell types, including T cells, B cells, monocytes, neutrophils, and dendritic cells. It is also found in brain, heart, kidney, liver, and other organs. The ligands of HVEM are LIGHT, BTLA, LTα, and CD160. HVEM activates NF-kB through the TNF-related cytokine LIGHT to serve as a costimulatory pathway during T cell activation. HVEM also functions as a ligand for the Ig superfamily members B and T lymphocyte attenuator (BTLA) and CD160 to deliver a coinhibitory signal and limit inflammatory responses initiated by T cells. HVEM plays an important role in regulating lymphocyte activation and homeostasis in immune responses.
    途径
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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