The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
CD226 (DNAM-1) is constitutively expressed on native CD8+ cells and on some CD4+ T cells, macrophages and NK cells. CD226 is involved in NK and T cell mediated cytotoxicity against certain tumors. CD155 and CD112 are the ligands for CD226. This antibody (480.1) is reported by the developer to partially block the binding of mouse CD155.