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- 抗原 See all PTPRJ 抗体
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PTPRJ antibody is conjugated to PE
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应用范围
- ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- 克隆位点
- A3
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product PTPRJ Primary Antibody
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anti-Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ) (AA 567-842) antibody
PTPRJ 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ) (AA 1061-1293) antibodyPTPRJ 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ) (AA 36-210) antibodyPTPRJ 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 1D2C11 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ) (AA 36-210) antibodyPTPRJ 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6F2E12 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ) (AA 865-970) antibodyPTPRJ 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ) (AA 140-370) antibodyPTPRJ 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ) (AA 38-137) antibodyPTPRJ 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6G11 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ) (AA 1-444) antibodyPTPRJ 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-CD148-05 unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ) (AA 1-444) antibody (Biotin)PTPRJ 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-CD148-05 Biotin
anti-Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ) (AA 1-444) antibody (APC)PTPRJ 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-CD148-05 APC
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
- 别名
- CD148 (PTPRJ 产品)
- 别名
- HAAP antibody, CD148 antibody, DEP1 antibody, HPTPeta antibody, R-PTP-ETA antibody, SCC1 antibody, AI450271 antibody, BET antibody, Byp antibody, DEP-1 antibody, PTPbeta2 antibody, Ptpb2 antibody, RPTPJ antibody, Scc-1 antibody, Scc1 antibody, PTPRJ antibody, acid phosphatase 1 antibody, protein tyrosine phosphatase, receptor type J antibody, protein tyrosine phosphatase, receptor type, J antibody, ACP1 antibody, PTPRJ antibody, Ptprj antibody, EUBREC_2762 antibody
- 背景
- CD148, a receptor-like protein tyrosine phosphatase also known as human protein tyrosine phosphatase-eta (HPTP-eta) or density-enhanced protein tyrosine phosphatase-1 (DEP-1), is involved in signal transduction in leucocytes and is thought to contribute to mechanisms of cellular differentiation. In lymphoid organs, CD148 was found to be widely expressed on B and T cells, granulocytes, macrophages, certain dendritic cells as well as mature thymocytes. The cellular level of CD148 was increased after in vitro activation of peripheral blood leucocytes. CD148 as a leucocyte activation marker and may be involved in the regulation of T cell activation. Leucocytes expressing CD148 are significantly upregulated in inflamed tissues and that a subset of these cells co-expresses the activation marker CD25. In non-lymphoid tissues, CD148 was found to be present on many epithelial cell types with glandular and/or endocrine differentiation as well as on fibrocytes, melanocytes and Schwann cells. Among non-hematopoietic cells, CD148 is expressed by characteristic types of epithelial and non-epithelial cells. Downregulation of CD148 might promote dedifferentiation and autonomous growth of such cells in malignant tumors.
- 途径
- EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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