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PTPRJ 抗体 (AA 140-370)

PTPRJ 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167504
发货至: 中国
  • 抗原 See all PTPRJ 抗体
    PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
    抗原表位
    • 12
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 140-370
    适用
    • 45
    • 17
    • 13
    • 1
    • 1
    宿主
    • 30
    • 19
    克隆类型
    • 30
    • 18
    多克隆
    标记
    • 22
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTPRJ antibody is un-conjugated
    应用范围
    • 36
    • 15
    • 15
    • 12
    • 10
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Receptor-type tyrosine-protein phosphatase eta protein (140-370AA)
    亚型
    IgG
    Top Product
    Discover our top product PTPRJ Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
    别名
    PTPRJ (PTPRJ 产品)
    别名
    HAAP antibody, CD148 antibody, DEP1 antibody, HPTPeta antibody, R-PTP-ETA antibody, SCC1 antibody, AI450271 antibody, BET antibody, Byp antibody, DEP-1 antibody, PTPbeta2 antibody, Ptpb2 antibody, RPTPJ antibody, Scc-1 antibody, Scc1 antibody, PTPRJ antibody, acid phosphatase 1 antibody, protein tyrosine phosphatase, receptor type J antibody, protein tyrosine phosphatase, receptor type, J antibody, ACP1 antibody, PTPRJ antibody, Ptprj antibody, EUBREC_2762 antibody
    背景

    Background: Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET (variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration, through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation, through KDR dephosphorylation. Negative regulator of EGFR signaling pathway, through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling.

    Aliases: CD 148 antibody, CD148 antibody, CD148 antigen antibody, Density enhanced phosphatase 1 antibody, Density-enhanced phosphatase 1 antibody, DEP 1 antibody, DEP-1 antibody, HPTP eta antibody, HPTPeta antibody, Human density enhanced phosphatase 1 antibody, Protein tyrosine phosphatase eta antibody, Protein tyrosine phosphatase receptor type J antibody, Protein tyrosine phosphatase receptor type J polypeptide antibody, Protein-tyrosine phosphatase eta antibody, Protein-tyrosine phosphatase receptor type J antibody, PTPJ antibody, Ptprj antibody, PTPRJ_HUMAN antibody, R PTP Eta antibody, R-PTP-eta antibody, R-PTP-J antibody, Receptor type tyrosine protein phosphatase eta antibody, Receptor-type tyrosine-protein phosphatase eta antibody, SCC 1 antibody, SCC1 antibody, susceptibility to colon cancer 1, mouse, homolog of antibody

    UniProt
    Q12913
    途径
    EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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