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CLEC9A 抗体 (PE)

CLEC9A 适用: 人 ICFC 宿主: 小鼠 Monoclonal 8F9 PE
产品编号 ABIN2662627
发货至: 中国
  • 抗原 See all CLEC9A 抗体
    CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CLEC9A antibody is conjugated to PE
    应用范围
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    Intracellular Flow Cytometry (ICFC)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    8F9
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CLEC9A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))
    别名
    CD370 (CLEC9A 产品)
    别名
    9830005G06Rik antibody, DNGR-1 antibody, DNGR1 antibody, UNQ9341 antibody, RGD1562513 antibody, C-type lectin domain family 9, member a antibody, C-type lectin domain containing 9A antibody, C-type lectin domain family 9, member A antibody, Clec9a antibody, CLEC9A antibody
    背景
    CD370 (CLEC9A), also known as DNGR1, is a type II transmembrane protein consisting of a single extracellular C-type lectin domain (CTLD) that is connected to the transmembrane domain by a stalk region, and an intracellular cytoplasmic tail with immunoreceptor tyrosine-based activation motif (ITAM). In humans, CLEC9A is strictly expressed on BDCA3-positive conventional dendritic cells (cDC) and CD16- monocytes. CLEC9A recognizes a ubiquitous preformed acid-labile protein associated ligand(s) that is exposed on necrotic cells. CLEC9A ligation is necessary for efficient cross-presentation of dead-cell-associated antigen by recruitment and activation of the tyrosine kinase Syk.
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