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CLEC9A 抗体 (PE)

CLEC9A 适用: 人 FACS 宿主: 小鼠 Monoclonal 8F9 PE
产品编号 ABIN7013960
发货至: 中国
  • 抗原 See all CLEC9A 抗体
    CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CLEC9A antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody 8F9 recognizes an extracellular epitope of CD370 / CLEC9A (DNGR1), a type II transmembrane protein functioning as an endocytic receptor on BDCA31+ dendritic cells and on a subset of CD14+ CD16- monocytes.
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    RBL-2H3 cells expressing human CLEC9A fused to an HA epitope
    克隆位点
    8F9
    亚型
    IgG2a
    Top Product
    Discover our top product CLEC9A Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))
    别名
    CD370 (CLEC9A 产品)
    别名
    9830005G06Rik antibody, DNGR-1 antibody, DNGR1 antibody, UNQ9341 antibody, RGD1562513 antibody, C-type lectin domain family 9, member a antibody, C-type lectin domain containing 9A antibody, C-type lectin domain family 9, member A antibody, Clec9a antibody, CLEC9A antibody
    背景
    C-type lectin domain containing 9A,CD370 / CLEC9A, also known as DNGR1, is a type II transmembrane glycoprotein with extracellular C-type lectin domain and intracellular ITAM-containing domain. Its expression is restricted to BDCA3+ conventional dendritic cells and to a subset of CD14+ CD16- monocytes. CD370 serves as a receptor for ubiquitous preformed acid-labile protein associated ligands that are exposed when the cell membrane is damaged, such as on necrotic cells. Its triggering by these ligands mediates recruitment and activation of the tyrosine kinase Syk and leads to their cross-presentation to the immune system.,CLEC9A, DNGR1, DNGR-1, UNQ9341
    基因ID
    283420
    UniProt
    Q6UXN8
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