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TACI 抗体 (Biotin)

TNFRSF13B 适用: 人 FACS 宿主: 大鼠 Monoclonal 1A1 Biotin
产品编号 ABIN2661017
发货至: 中国
  • 抗原 See all TACI (TNFRSF13B) 抗体
    TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
    适用
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    宿主
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    大鼠
    克隆类型
    • 35
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    单克隆
    标记
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    This TACI antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    克隆位点
    1A1
    亚型
    IgG2a kappa
    Top Product
    Discover our top product TNFRSF13B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
    别名
    CD267 (TNFRSF13B 产品)
    别名
    CD267 antibody, CVID antibody, CVID2 antibody, RYZN antibody, TACI antibody, TNFRSF14B antibody, TNFRSF13B antibody, 1200009E08Rik antibody, Taci antibody, TNF receptor superfamily member 13B antibody, tumor necrosis factor receptor superfamily, member 13b antibody, TNFRSF13B antibody, Tnfrsf13b antibody
    背景
    TACI, Transmembrane Activator CAML (calcium modulator and cyclophilin ligand) Interactor, is a 32 kD type III transmembrane protein. It belongs to TNF receptor superfamily, known as TNFRSF member 13B (TNFRSF13B) or CD267. TACI is expressed on B cells, and myeloma cells. TACI contains 2 cysteine-rich domains (CRDs). Recent studies, however, have shown that another shorter form (TACI_d2) of TACI exists wherein the N-terminal CRD is removed by alternative splicing. TACI_d2 contains full affinity for its ligands. Several proteins (BAFF/BLys, APRIL, Syndecan-2) have been identified as TACI ligands. The interaction of TACI with its ligands induces activation of the transcription factors NFAT, AP1, and NF-κ B and plays a crucial role in humoral immunity by negative regulation of B cell proliferation and survival.
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