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TACI 抗体

TNFRSF13B 适用: 人 FACS 宿主: 大鼠 Monoclonal 1A1 unconjugated
产品编号 ABIN4888498
发货至: 中国
  • 抗原 See all TACI (TNFRSF13B) 抗体
    TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
    适用
    • 32
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    宿主
    • 33
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    大鼠
    克隆类型
    • 35
    • 20
    单克隆
    标记
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    This TACI antibody is un-conjugated
    应用范围
    • 41
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    Flow Cytometry (FACS)
    特异性
    The rat monoclonal antibody 1A1 recognizes an extracellular epitope of CD267 / TACI, a 32 kDa type III transmembrane protein expressed by B cells and possibly by some activated T cells.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-G affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    CD267-transfected RBL cells
    克隆位点
    1A1
    亚型
    IgG2a kappa
    Top Product
    Discover our top product TNFRSF13B Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
    别名
    CD267 / TACI (TNFRSF13B 产品)
    别名
    CD267 antibody, CVID antibody, CVID2 antibody, RYZN antibody, TACI antibody, TNFRSF14B antibody, TNFRSF13B antibody, 1200009E08Rik antibody, Taci antibody, TNF receptor superfamily member 13B antibody, tumor necrosis factor receptor superfamily, member 13b antibody, TNFRSF13B antibody, Tnfrsf13b antibody
    背景
    TNF receptor superfamily member 13B,CD267 / TACI (transmembrane activator calcium modulator and cyclophilin ligand interactor), a TNFR superfamily transmembrane protein, is expressed on B cells (predominantly on CD27+ memory cells), multiple myeloma cells and B cell chronic lymphocytic leukemia (B-CLL). Its triggering leads to activation of the transcription factors NFAT, AP1, and NF-kappa-B. It plays a crucial role in humoral immunity. Mutations in CD267 are associated with common variable immunodeficiency and IgA deficiency.,RYZN, TACI, CVID2, IGAD2, TNFRSF14B
    基因ID
    23495
    UniProt
    O14836
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