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- 抗原 See all HVEM (TNFRSF14) 抗体
- HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HVEM antibody is conjugated to PE-Cy7
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- 产品特性
- The 122 antibody recognizes human HVEM also known as herpesvirus entry mediator A, tumor necrosis factor receptor superfamily, member 14, TNFRSF14, and tumor necrosis factor receptor like 2. HVEM, a member of the TNFR superfamily, is a type I transmembrane protein containing 2 TNF receptor domains with a predicted molecular weight of approximately 30 kD. HVEM is widely expressed in blood vessels, brain, heart, kidney, liver, lung, prostate, spleen, thymus and other organs. Resting T cells and naive and memory B cells express high levels of HVEM as well. In humans, HVEM is not expressed in germinal center B cells. Immature dendritic cells express high levels of HVEM that is downregulated upon maturation. HVEM plays an important role in herpes simplex virus pathogenesis by enhancing entry into cells. Signaling through HVEM activates JNK1, NF-κB and AP-1 to control gene expression in response to infection or cellular stress and activate the immune response. HVEM binds to LIGHT and has also been shown to associate with several other proteins including TRAF1, TRAF2, TRAF3, TRAF5, B and T lymphocyte associated protein (BTLA), and estrogen receptor alpha.
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
- 克隆位点
- 122
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TNFRSF14 Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (AA 38-283) antibody
TNFRSF14 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G6-2C7 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (AA 41-209) antibodyTNFRSF14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) antibodyTNFRSF14 适用: 小鼠 WB, FACS, IP, BP, Func 宿主: 兔 Chimeric HMHV-1B18 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (AA 39-202) antibodyTNFRSF14 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM131 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (AA 38-284) antibodyTNFRSF14 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2G6-2C7 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (AA 1-283) antibodyTNFRSF14 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (C-Term) antibodyTNFRSF14 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (Internal Region) antibodyVerified TNFRSF14 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (AA 210-236) antibodyTNFRSF14 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21524 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (AA 216-245), (Middle Region) antibodyTNFRSF14 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))
- 别名
- CD270 (TNFRSF14 产品)
- 别名
- ATAR antibody, CD270 antibody, HVEA antibody, HVEM antibody, LIGHTR antibody, TR2 antibody, Atar antibody, HveA antibody, Hvem antibody, Tnfrs14 antibody, TNF receptor superfamily member 14 antibody, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) antibody, Tnfrsf14 antibody, TNFRSF14 antibody
- 物质类
- Viral Protein
- 途径
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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