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- 抗原 See all CSF3R 抗体
- CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CSF3R antibody is conjugated to APC
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
- 克隆位点
- LMM741
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CSF3R Primary Antibody
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anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 26-138) antibody
CSF3R 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 271-428) antibodyCSF3R 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-187) antibodyCSF3R 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 3G10G2 unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 117-337) antibodyCSF3R 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 101-200) antibodyCSF3R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 1-836) antibodyCSF3R 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) antibodyCSF3R 适用: 人 FACS 宿主: 小鼠 Monoclonal LMM741 unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 420-543) antibodyCSF3R 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 252-280) antibodyCSF3R 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23568 unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 259-288), (Middle Region) antibodyCSF3R 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
- 别名
- CD114 (CSF3R 产品)
- 别名
- CD114 antibody, GCSFR antibody, Cd114 antibody, Csfgr antibody, G-CSF-R antibody, G-CSFR antibody, CSF3R antibody, gcsfr antibody, cd114 antibody, colony stimulating factor 3 receptor antibody, colony stimulating factor 3 receptor (granulocyte) antibody, colony stimulating factor 3 receptor L homeolog antibody, granulocyte colony-stimulating factor receptor antibody, CSF3R antibody, Csf3r antibody, csf3r antibody, csf3r.L antibody, LOC100433338 antibody
- 背景
- CD114 is the receptor of the colony stimulating factor 3 (CSF3, G-CSF), consist of two 130 kD, type I transmembrane chains that form a homodimer. The extracellular domain consists of an immunoglobulin-like domain, a cytokine receptor homologue domain, and three fibronectin type III repeats. CD114 is expressed in all stages of granulocyte differentiation and in monocytes, platelets, endothelial cells, placenta and trophoblasts. The binding of CSF3, results in the activation of many signaling molecules such as Syk, Lyn, Jak1, Jak2, Tyk2, SOCS3, SOCS1, STAT5, and Shp1, resulting in the expression of different target genes that will increase neutrophil precursor survival, proliferation and maturation. In mature neutrophils, it increases survival, superoxide anion generation, arachidonic acid release, production of myeloperoxidase and leukocyte alkaline phosphatase (LAP).
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