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- 抗原 See all LCK 抗体
- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LCK antibody is conjugated to Alexa Fluor 647
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
- 克隆位点
- Lck-01
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product LCK Primary Antibody
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anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 WB, ELISA, IP, RNAi 宿主: 小鼠 Monoclonal 3F7-F5 unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-240) antibodyLCK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 22-36) antibodyLCK 适用: 人 WB, FACS, IP, ICC 宿主: 小鼠 Monoclonal LCK-01 unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 23-52) antibodyLCK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibodyLCK 适用: 人 ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 468-506), (C-Term) antibodyLCK 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 480-509) antibodyLCK 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 421-509) antibodyLCK 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibodyLCK 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-100) antibodyLCK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C
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- 抗原
- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
- 别名
- Lck (LCK 产品)
- 别名
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zgc:136695 antibody, LCK antibody, Hck-3 antibody, Lsk antibody, Lskt antibody, p56
antibody, p56Lck antibody, LSK antibody, YT16 antibody, p56lck antibody, pp58lck antibody, P56LCK antibody, tkl antibody, Lck1 antibody, Lcktkr antibody, LCK proto-oncogene, Src family tyrosine kinase antibody, lymphocyte protein tyrosine kinase antibody, lck antibody, LCK antibody, Lck antibody - 背景
- Lck is a 56 kD tyrosine protein kinase and a member of the src subfamily that contains both an SH2 and SH3 domain. Alternatively spliced isoforms of Lck have been reported. Lck is a cytoplasmic protein bound to CD4 and CD8 in T cells that participate in antigen-induced T cell activation through phosphorylation of the T cell receptor zeta chain. Lck is activated upon T cell receptor engagement and is involved in the onset of cell cycle progression induced by interleukin-2. Phosphorylation by Csk downregulates the activity of Lck. In addition to CD4 and CD8, Lck has been reported to interact with PI3K through its SH3 domain and tyrosine phosphorylated KHDRBS1/p70 through its SH2 domain. In addition, Lck has been shown to associate with the SAP transmembrane tyrosine phosphatase.
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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