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CCR3 抗体 (Alexa Fluor 647)

CCR3 适用: 小鼠 WB, FACS, IHC 宿主: 大鼠 Monoclonal J073E5 Alexa Fluor 647
产品编号 ABIN2657148
发货至: 中国
  • 抗原 See all CCR3 抗体
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    适用
    • 74
    • 30
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    小鼠
    宿主
    • 53
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    大鼠
    克隆类型
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    单克隆
    标记
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    This CCR3 antibody is conjugated to Alexa Fluor 647
    应用范围
    • 49
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
    克隆位点
    J073E5
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CCR3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    别名
    CD193 (CCR3 产品)
    别名
    CC-CKR-3 antibody, CD193 antibody, CKR3 antibody, CMKBR3 antibody, CC-CKR3 antibody, Cmkbr1l2 antibody, Cmkbr3 antibody, C-C motif chemokine receptor 3 antibody, chemokine (C-C motif) receptor 3 antibody, CCR3 antibody, Ccr3 antibody
    背景
    CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-α receptor like-2, and eotaxin receptor, is a member of the G protein-coupled, seven transmembrane receptor family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CD193 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CD193 is expressed on mouse eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, hematopoietic progenitor cells, and keratinocytes. It is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CD193 also function as a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CD193 has been shown to inhibit HIV infection in some cell types.
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