(1 reference)-
- 抗原 See all CCR3 抗体
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CCR3 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody 5E8 recognizes an extracellular epitope of CD193 (chemokine receptor 3), an approximately 41 kDa protein expressed above all in eosinophils and basophils.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- human CD193 transfectants
- 克隆位点
- 5E8
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product CCR3 Primary Antibody
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anti-Chemokine (C-C Motif) Receptor 3 (CCR3) antibody
CCR3 适用: 人 WB, ELISA, FACS, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 8E9H10 unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 251-355) antibodyCCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 306-355) antibodyCCR3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (N-Term) antibodyCCR3 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (Extracellular Domain) antibodyCCR3 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 5-28) antibodyCCR3 适用: 人, 小鼠 WB, IHC, IHC (p), ICC 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) antibodyCCR3 适用: 人 FACS 宿主: 小鼠 Monoclonal 5E8 unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "NADPH oxidase-independent formation of extracellular DNA traps by basophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5314-23, (2014) (PubMed).
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: "NADPH oxidase-independent formation of extracellular DNA traps by basophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5314-23, (2014) (PubMed).
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- 抗原
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
- 别名
- CD193 (CCR3 产品)
- 别名
- CC-CKR-3 antibody, CD193 antibody, CKR3 antibody, CMKBR3 antibody, CC-CKR3 antibody, Cmkbr1l2 antibody, Cmkbr3 antibody, C-C motif chemokine receptor 3 antibody, chemokine (C-C motif) receptor 3 antibody, CCR3 antibody, Ccr3 antibody
- 背景
- C-C motif chemokine receptor 3,CD193 / CCR3 is a G-protein coupled receptor for several chemokines, namely CCL11 (eotaxin), CCL26 (eotaxin-3), CCL7 (MCP-4), or CCL5 (RANTES). It is highly expressed on eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. CD193 is the key eosinophil chemokine receptor responsible for regulation of eosinophil migration and function. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.,CCR3, CKR3, CMKBR3, CC-CKR-3
- 基因ID
- 1232
- UniProt
- P51677
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