NR4A1 抗体 (Alexa Fluor 594)
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- 抗原 See all NR4A1 抗体
- NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NR4A1 antibody is conjugated to Alexa Fluor 594
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应用范围
- Flow Cytometry (FACS), Blocking Reagent (BR), Immunoprecipitation (IP)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions. The solution is free of unconjugated Alexa Fluor® 594.
- 克隆位点
- 1E10A15
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product NR4A1 Primary Antibody
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anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (N-Term) antibody
NR4A1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (AA 1-170) antibodyNR4A1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (Ser351) antibodyNR4A1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (C-Term) antibodyNR4A1 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (AA 351-450) antibodyNR4A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (Ser474) antibodyNR4A1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (AA 251-266) antibodyNR4A1 适用: 人 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (AA 324-373) antibodyNR4A1 适用: 人, 犬, Cow, 马, 兔, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (AA 1-598) antibodyNR4A1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (Internal Region) antibodyVerified NR4A1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C
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- 抗原
- NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
- 别名
- Nur77 (NR4A1 产品)
- 别名
- GFRP1 antibody, HMR antibody, N10 antibody, NAK-1 antibody, NGFIB antibody, NP10 antibody, NUR77 antibody, TR3 antibody, NGFI-B antibody, Gfrp antibody, Hbr-1 antibody, Hbr1 antibody, Hmr antibody, TIS1 antibody, nur77 antibody, Ngfi-b antibody, Nur77 antibody, nuclear receptor subfamily 4 group A member 1 antibody, nuclear receptor subfamily 4, group A, member 1 antibody, NR4A1 antibody, Nr4a1 antibody
- 背景
- Nur77, a transcription factor belonging to a superfamily of orphan nuclear receptors, has been shown to activate a subset of genes containing NGFI-B response element (NBRE). Nur77 expression is upregulated in response to stimuli of numerous growth factors, mitogens, and inflammatory substances, indicating that Nur77 has regulatory roles in cell growth and inflammation. Nur77 has also been shown to participate in programmed cell death through mitochondrial targeting and interaction with Bcl-2. In the endocrine system, Nur77 has been reported to participate in regulating production of steroidogenic enzymes. Nur77 and NOR-1 double knockout mice develop acute myeloid leukemia, suggesting that Nur77 plays a role in regulating differentiation of myeloid progenitor cells.
- 途径
- Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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