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NR4A1 抗体 (N-Term)

NR4A1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777511
发货至: 中国
  • 抗原 See all NR4A1 抗体
    NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
    抗原表位
    • 22
    • 16
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 82
    • 41
    • 38
    • 9
    • 8
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠
    宿主
    • 82
    • 2
    • 2
    克隆类型
    • 81
    • 5
    多克隆
    标记
    • 52
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NR4A1 antibody is un-conjugated
    应用范围
    • 65
    • 31
    • 19
    • 15
    • 14
    • 14
    • 14
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    GTPAPSPGPR DHLASDPLTP EFIKPTMDLA SPEAAPAAPT ALPSFSTFMD
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against NR4A1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human NR4A1
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 598 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bian, Chen, Yang, Li, Zhang, Zhang, Wang, Zhao, Zhang, Chen, Zheng, Sun, Wang, Chien, Wu: "Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation." in: Nature communications, Vol. 8, pp. 14420, (2017) (PubMed).

  • 抗原
    NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
    别名
    NR4A1 (NR4A1 产品)
    别名
    GFRP1 antibody, HMR antibody, N10 antibody, NAK-1 antibody, NGFIB antibody, NP10 antibody, NUR77 antibody, TR3 antibody, NGFI-B antibody, Gfrp antibody, Hbr-1 antibody, Hbr1 antibody, Hmr antibody, TIS1 antibody, nur77 antibody, Ngfi-b antibody, Nur77 antibody, nuclear receptor subfamily 4 group A member 1 antibody, nuclear receptor subfamily 4, group A, member 1 antibody, NR4A1 antibody, Nr4a1 antibody
    背景
    NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.
    Alias Symbols: HMR, N10, TR3, NP10, GFRP1, NAK-1, NGFIB, NUR77
    Protein Interaction Partner: KRTAP10-5, KRTAP10-1, LONRF1, PGBD1, BCL2L10, CDKN2D, BCL2A1, BCL2, TUBB4A, VASP, ANKIB1, CUTA, NFKB1, SMAD3, LSS, HADHA, GLUD1, GK, CPT1A, SERPING1, ABCC6, ABCC13, SOCS4, ABCG8, DIABLO, HCVgp1, ABCA5, CHEK2, SUGT1, PRDX4, PRDX6, CHD1L, ABCB11, ARHGEF5, U
    Protein Size: 598
    分子量
    66 kDa
    基因ID
    3164
    NCBI登录号
    NM_173157, NP_775180
    UniProt
    P22736
    途径
    Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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