KRT14 抗体
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- 抗原 See all KRT14 抗体
- KRT14 (Keratin 14 (KRT14))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KRT14 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Keratin 14 protein. (region surrounding Ser5)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product KRT14 Primary Antibody
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anti-Keratin 14 (KRT14) antibody
KRT14 适用: 人 WB, IHC, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) (AA 1-484) antibodyKRT14 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人, 大鼠, 小鼠 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal LL002 unconjugated
anti-Keratin 14 (KRT14) (AA 351-472) antibodyKRT14 适用: 人, 大鼠, 小鼠, Pig IHC, FACS, StM 宿主: 小鼠 Monoclonal KRT14-2375 unconjugated
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人, 大鼠, Pig, 犬 WB, IHC, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal RCK107 unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Keratin 14 (KRT14) (AA 276-303) antibodyKRT14 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- KRT14 (Keratin 14 (KRT14))
- 别名
- Cytokeratin 14 (KRT14 产品)
- 别名
- CK14 antibody, EBS3 antibody, EBS4 antibody, K14 antibody, NFJ antibody, AI626930 antibody, Krt-1.14 antibody, Krt1-14 antibody, Ka14 antibody, ouro2 antibody, keratin 14 antibody, keratin 14, type I L homeolog antibody, KRT14 antibody, Krt14 antibody, krt14.L antibody
- 背景
- Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed in pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85 % of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The α-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins are useful markers of tissue differentiation, and in addition they aid in the characterization of malignant tumors. In Bowen's disease, the characteristic malignancy of the epidermis exhibits distinct expression patterns of Cytokeratin 14. Mutations in the gene encoding human Cytokeratin 14 lead to epidermolysis bullosa simplex, an inheritied skin disorder characterized by skin blistering due to basal keratinocyte fragility.Synonyms: CK14, Cytokeratin-14, K14, KRT14, Keratin 14, Keratin Type I Cytoskeletal 14
- 分子量
- approx. 52 kDa
- 基因ID
- 3861
- NCBI登录号
- NP_000517
- UniProt
- P02533
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