FGFR3 抗体
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- 抗原 See all FGFR3 抗体
- FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FGFR3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of FGFR3 protein. (region surrounding Trp153)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product FGFR3 Primary Antibody
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anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 529-694) antibody
FGFR3 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2H10B4 unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 166-375) antibodyFGFR3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 39-138) antibodyFGFR3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 23-375) antibodyFGFR3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (C-Term) antibodyFGFR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 529-694) antibodyFGFR3 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 1E3F9 unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) antibodyFGFR3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 110-129), (N-Term) antibodyFGFR3 适用: 人, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 131-180) antibodyFGFR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (AA 776-806) antibodyFGFR3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
- 别名
- CD333 / FGFR3 (FGFR3 产品)
- 别名
- FGFR3 antibody, LOC100034114 antibody, ACH antibody, CD333 antibody, CEK2 antibody, HSFGFR3EX antibody, JTK4 antibody, FR3 antibody, Fgfr-3 antibody, Flg-2 antibody, HBGFR antibody, Mfr3 antibody, sam3 antibody, fc27h01 antibody, wu:fc27h01 antibody, fibroblast growth factor receptor 3 antibody, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog antibody, FGFR3 antibody, fgfr3.S antibody, Fgfr3 antibody, fgfr3 antibody
- 背景
- Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors.These include the Flg receptor or FGFR-1, the Bek receptor (or FGFR-2), FGFR-3, FGFR- 4, FGFR-5 and FGFR-6. These receptors usually contain an extracellular ligandbinding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. The gene encoding human Bek (also designated K-sam) maps to chromosome 10q26 and is alternatively spliced to produce several isoforms. Heterogeneous mutations in Bek are associated with a range of craniosynostosis syndromes including Pfeiffer syndrome, Crouzon syndrome, Jackson-Weiss syndrome and Apert syndrome.Synonyms: FGFR-3, Fibroblast growth factor receptor 3, JTK4
- 分子量
- approx. 95 kDa
- 基因ID
- 2261
- NCBI登录号
- NP_000133
- UniProt
- P22607
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
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