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ELK1 抗体

ELK1 适用: 人, 小鼠, 大鼠 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265399
发货至: 中国
  • 抗原 See all ELK1 抗体
    ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 145
    • 10
    克隆类型
    • 134
    • 22
    多克隆
    标记
    • 83
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    This ELK1 antibody is un-conjugated
    应用范围
    • 108
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    • 17
    • 7
    • 5
    • 5
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    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of ELK1 protein (region surrounding Ser383).
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product ELK1 Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. IHC: 1: 50approx. 1: 200. IP: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
    别名
    ELK1 (ELK1 产品)
    别名
    Elk-1 antibody, Xelk antibody, Xelk-1 antibody, elk-1 antibody, elk1 antibody, ELK1, ETS transcription factor antibody, ELK1, member of ETS oncogene family antibody, ETS domain-containing protein Elk-1 antibody, ELK1, member of ETS oncogene family S homeolog antibody, ELK1 antibody, Elk1 antibody, Tsp_02690 antibody, elk1 antibody, elk1.S antibody
    背景
    Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1-3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element.Synonyms: ETS domain-containing protein Elk-1, Elk-1
    分子量
    approx. 45 kDa
    基因ID
    2002
    NCBI登录号
    NP_001107595
    UniProt
    P19419
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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