CDC6 抗体
-
- 抗原 See all CDC6 抗体
- CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CDC6 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of CDC6 protein (region surrounding Val48).
- 交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product CDC6 Primary Antibody
-
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (AA 1-560) antibody
CDC6 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (AA 1-326) antibodyCDC6 适用: 人, 小鼠 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (AA 1-141) antibodyCDC6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) antibodyCDC6 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (AA 147-549) antibodyCDC6 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (AA 434-533) antibodyCDC6 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (Ser219) antibodyCDC6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (Internal Region) antibodyVerified CDC6 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (pSer54) antibodyCDC6 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (pSer54) antibodyCDC6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7524 unconjugated
-
- 应用备注
-
ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
- 别名
- CDC6 (CDC6 产品)
- 别名
- CDC18L antibody, HsCDC18 antibody, HsCDC6 antibody, cell division cycle 6 antibody, CDC6 antibody, Cdc6 antibody
- 背景
- Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with HSP 90. Cdc34, Cdc27 and Cdc16 function as ubiquitinconjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphasepromoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.Synonyms: CDC18L, CDC6-related protein, Cdc18-related protein, Cell division control protein 6 homolog, HsCDC6, HsCdc18, p62(cdc6)
- 分子量
- approx. 62 kDa
- 基因ID
- 990
- NCBI登录号
- NP_001245
- UniProt
- Q99741
- 途径
- DNA Replication, Synthesis of DNA
-
