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CDC6 抗体 (AA 147-549)

CDC6 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043500
发货至: 中国
  • 抗原 See all CDC6 抗体
    CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
    抗原表位
    • 23
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-549
    适用
    • 94
    • 26
    • 17
    • 4
    • 1
    • 1
    人, 大鼠
    宿主
    • 83
    • 11
    • 1
    克隆类型
    • 74
    • 21
    多克隆
    标记
    • 46
    • 7
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDC6 antibody is un-conjugated
    应用范围
    • 70
    • 44
    • 24
    • 13
    • 12
    • 10
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Cell division control protein 6 homolog(CDC6) detection. Tested with WB, IHC-P in Human,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Cell division control protein 6 homolog(CDC6) detection. Tested with WB, IHC-P in Human,Rat.
    Gene Name: cell division cycle 6
    Protein Name: Cell division control protein 6 homolog
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human Cdc6 recombinant protein (Position: V147-A549). Human Cdc6 shares 87.3% amino acid (aa) sequence identity with mouse Cdc6.
    亚型
    IgG
    Top Product
    Discover our top product CDC6 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
    别名
    CDC6 (CDC6 产品)
    别名
    CDC18L antibody, HsCDC18 antibody, HsCDC6 antibody, cell division cycle 6 antibody, CDC6 antibody, Cdc6 antibody
    背景
    Cell division control ptotein 6 homolog, also called CDC18L or CDC6, is a protein that in humans is encoded by the CDC6 gene. By analysis of somatic cell hybrids and by fluorescence in situ hybridization, this gene is mapped to 17q21.2. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. And this protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. This gene is involved in the initiation of DNA replication.

    Synonyms: Cdc 18L antibody|Cdc 6 antibody|CDC18 (cell division cycle 18, S.pombe, homolog) like antibody|CDC18 (S.pombe) antibody|Cdc18 related protein antibody|CDC18(S.pombe) antibody| Cdc18-related protein antibody|Cdc18L antibody|cdc6 antibody|CDC6 cell division cycle 6 homolog antibody|CDC6 related protein antibody|CDC6-related protein antibody| CDC6_HUMAN antibody|Cdc6p antibody|Cell Cycle Controller antibody|CELL CYCLE CONTROLLER CDC6 antibody| Cell division control protein 6 antibody|Cell division control protein 6 homolog antibody| Cell Division Cycle 18 antibody|Cell division cycle 6 homolog (S. cerevisiae) antibody|Cell division cycle 6 homolog antibody|HsCDC 6 antibody|HsCDC18 antibody|HsCDC6 antibody|p62 antibody|p62(cdc 6) antibody|p62(cdc6) antibody
    基因ID
    990
    UniProt
    Q99741
    途径
    DNA Replication, Synthesis of DNA
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