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IRF7 抗体 (Middle Region)

IRF7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265130
发货至: 中国
  • 抗原 See all IRF7 抗体
    IRF7 (Interferon Regulatory Factor 7 (IRF7))
    抗原表位
    • 17
    • 17
    • 15
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 70
    • 55
    • 54
    • 17
    • 8
    • 3
    • 2
    • 2
    • 1
    宿主
    • 69
    • 2
    克隆类型
    • 58
    • 13
    多克隆
    标记
    • 24
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 1
    This IRF7 antibody is un-conjugated
    应用范围
    • 50
    • 18
    • 15
    • 14
    • 14
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB)
    特异性
    This antibody reacts to Interferon regulatory factor 7 (IRF7).
    纯化方法
    Purified
    免疫原
    Rabbit polyclonal IRF7 antibody was raised against a peptide corresponding to 14 amino acids near the center of human IRF7
    亚型
    IgG
    Top Product
    Discover our top product IRF7 Primary Antibody
  • 应用备注
    Western Blot: 1 - 2 μg/mL. Expressed predominantly in spleen, thymus and peripheral blood leukocytes, IRF7 islocated in the nucleus and cytoplasm. The phosphorylated and active form accumulatesselectivly in the nucleus.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原
    IRF7 (Interferon Regulatory Factor 7 (IRF7))
    别名
    IRF7 (IRF7 产品)
    别名
    wu:fl24c03 antibody, zgc:66043 antibody, zgc:77947 antibody, IRF7 antibody, irf7 antibody, IRF-7H antibody, IRF7A antibody, IRF7B antibody, IRF7C antibody, IRF7H antibody, interferon regulatory factor 7 antibody, irf7 antibody, IRF7 antibody, Irf7 antibody
    背景
    Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling (3,4). There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.Synonyms: IRF-7, Interferon regulatory factor 7
    基因ID
    3665
    NCBI登录号
    NP_001563
    UniProt
    Q92985
    途径
    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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