电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Stargazin 抗体

CACNG2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265040
发货至: 中国
  • 抗原 See all Stargazin (CACNG2) 抗体
    Stargazin (CACNG2) (Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2))
    适用
    • 30
    • 25
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 25
    • 20
    • 1
    克隆类型
    • 23
    • 23
    多克隆
    标记
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Stargazin antibody is un-conjugated
    应用范围
    • 38
    • 13
    • 13
    • 10
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to CACNG2.
    纯化方法
    Purified
    免疫原
    Synthetic peptide derived from the rat calcium channel gamma2 subunit conjugated to KLH
    亚型
    IgG
    Top Product
    Discover our top product CACNG2 Primary Antibody
  • 应用备注
    Western Blot: 5 - 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原
    Stargazin (CACNG2) (Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2))
    别名
    CACNG2 (CACNG2 产品)
    别名
    cacng2 antibody, zgc:64200 antibody, CACNG2 antibody, stargazin antibody, AW060990 antibody, B230105C07Rik antibody, B930041E13Rik antibody, stargazer antibody, stg antibody, wag antibody, waggler antibody, Ipr328 antibody, MRD10 antibody, calcium voltage-gated channel auxiliary subunit gamma 2 antibody, calcium channel, voltage-dependent, gamma subunit 2a antibody, calcium channel, voltage-dependent, gamma subunit 2 antibody, CACNG2 antibody, cacng2a antibody, cacng2 antibody, Cacng2 antibody
    背景
    Voltage-dependent calcium channels (VDCCs) are large (>400 kDa) heteromers which contain, minimally, three core subunits alpha1, alpha2/delta, beta in a 1:1:1 stoichiometry. Expression of VDCC gene products in Xenopus oocytes, or transfected cells shows that the alpha1 subunits contain the ion channel pore while the auxiliary alpha2/delta and beta subunits confer optimal cell surface expression and channel kinetics1. Until recently, the only exception to the above paradigm was the skeletal muscle VDCC, which, in addition to the alpha1, alpha2/delta, beta core motif, also has an additional tightly associated integral membrane glycoprotein subunit termed gamma 1. Upon co-expression with the alpha1.1, alpha2/delta1, beta1a subunits of the skeletal muscle VDCC, gamma subunits alter the peak currents, and the kinetics of channel activation and inactivation with the overall effect being a normalisation of currents to those resembling the endogenous channel2. Together, these results suggest that gamma subunits modulate skeletal muscle VDCCs by stabilising their conformation. The gamma 2 subunits, or stargazin, the product of a gene mutated in the stargazer mouse, is a homolog of the gamma 1 channel and is selectively expressed in the brain. It is considered to be a putative neuronal Ca2+ channel subtype mainly based on its homology to the gamma 1.Synonyms: Neuronal voltage-gated calcium channel gamma-2 subunit, TARP gamma-2, Transmembrane AMPAR regulatory protein gamma-2, Voltage-dependent calcium channel gamma-2 subunit
    基因ID
    10369
    NCBI登录号
    NP_006069
    UniProt
    Q9Y698
    途径
    Skeletal Muscle Fiber Development
You are here:
客服