Stargazin 抗体 (AA 203-323)
Quick Overview for Stargazin 抗体 (AA 203-323) (ABIN1686631)
抗原
See all Stargazin (CACNG2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 203-323
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特异性
- Detects ~35-55 kDa. Does not cross-react with TARPGamma3.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 203-323 (Cytoplasmic C-terminus) of rat TARPGamma2
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亚型
- IgG2a
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应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN1686631 was sufficient for detection of TARP Gamma2/4/8 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C
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: "Coexpressed auxiliary subunits exhibit distinct modulatory profiles on AMPA receptor function." in: Neuron, Vol. 83, Issue 3, pp. 601-15, (2014) (PubMed).
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: "Coexpressed auxiliary subunits exhibit distinct modulatory profiles on AMPA receptor function." in: Neuron, Vol. 83, Issue 3, pp. 601-15, (2014) (PubMed).
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- Stargazin (CACNG2) (Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2))
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别名
- Stargazin
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背景
- Stargazin belongs to a group called voltage gated calcium channels (VGCCs) which are present in most excitable cells. Stargazin is thought to stabilize the calcium channel in an inactivated (closed) state. There are five high voltage activated calcium channel types (L, N, P, Q, and R) and one low voltage activated channel type (T). Each of these channels exists as a heteromultimer of a1, b, a2/ d and g subunits with the voltage activated calcium channel function carried by the a subunits. VGCCs exert spatial and temporal control over cellular calcium concentrations and serve to modulate neurotransmitter release, hormone secretion, muscle contraction, electrical activity, cell metabolism and proliferation, gene expression, and neuronal survival.
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基因ID
- 84347
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NCBI登录号
- NP_445803
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UniProt
- Q71RJ2
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途径
- Skeletal Muscle Fiber Development
抗原
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