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BAX 抗体 (Isoform beta)

BAX 适用: 小鼠 IP 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN265017
发货至: 中国
  • 抗原 See all BAX 抗体
    BAX (BCL2-Associated X Protein (BAX))
    抗原表位
    • 39
    • 32
    • 19
    • 18
    • 15
    • 11
    • 10
    • 10
    • 9
    • 8
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    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 172-199, Isoform beta
    适用
    • 257
    • 153
    • 142
    • 46
    • 31
    • 27
    • 25
    • 18
    • 17
    • 10
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 168
    • 96
    • 3
    • 2
    绵羊
    克隆类型
    • 181
    • 88
    多克隆
    标记
    • 141
    • 16
    • 13
    • 12
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
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    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAX antibody is un-conjugated
    应用范围
    • 241
    • 112
    • 72
    • 66
    • 53
    • 52
    • 52
    • 42
    • 42
    • 13
    • 12
    • 8
    • 5
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunoprecipitation (IP)
    特异性
    This antibody reacts to Bax-beta.
    纯化方法
    Purified
    免疫原
    Synthetic peptide corresponding to amino acids 172 to 199 of the Bax beta protein
    亚型
    IgG
    Top Product
    Discover our top product BAX Primary Antibody
  • 应用备注
    Immunoprecipitation. Will NOT detect denatured protein by Western blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原
    BAX (BCL2-Associated X Protein (BAX))
    别名
    Bax (BAX 产品)
    别名
    BAX-ALPHA antibody, bax-A antibody, xBax antibody, xlbax antibody, BAX antibody, bax antibody, fj16e01 antibody, wu:fc50b10 antibody, wu:fj16e01 antibody, BCL2L4 antibody, zgc:112983 antibody, BCL2 associated X, apoptosis regulator antibody, BCL2-associated X protein L homeolog antibody, BCL2-associated X protein antibody, bcl2-associated X protein, a antibody, bcl2-associated X protein, b antibody, BAX antibody, bax.L antibody, bax antibody, baxa antibody, Bax antibody, baxb antibody
    背景
    Bax-beta is encoded by a 1.5 kb RNA species created by the retention of intron 5 in the bax mRNA transcript. The exon4/intron5 splice junction is evolutionarily conserved and is found in both the human and mouse bax coding regions. The 630 bp intron 5 contributes 60 amino acids to the Bax-beta protein before a stop codon is encountered during translation. The Bax-beta protein is 24 kDa in size and although it contains the BH1, BH2, and BH3 domains identical to Bax, it has a unique carboxyl terminus and does not have a hydrophobic transmembrane domain (Oltvai et al., 1993). Bax-beta mRNA has been found in many mouse tissues using RT-PCR. It is found co-expressed with Bax-alpha in lung, stomach, kidney, thymus, lymph node, bone marrow, pancreas, and spleen. Bax-beta mRNA was very abundant in brain and duodenum with almost no Bax-alpha mRNA detected in these tissues (Oltvai et al., 1993).Synonyms: Apoptosis regulator BAX, BCL2-associated X protein, BCL2L4, Bcl-2-like protein 4, Bcl2-L-4
    基因ID
    12028
    NCBI登录号
    NP_031553
    UniProt
    Q07813
    途径
    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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