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CCR8 抗体 (Extracellular Loop)

CCR8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265001
发货至: 中国
  • 抗原 See all CCR8 抗体
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    抗原表位
    • 14
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 183-201, Extracellular Loop
    适用
    • 48
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 42
    • 5
    • 4
    • 1
    克隆类型
    • 45
    • 7
    多克隆
    标记
    • 32
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR8 antibody is un-conjugated
    应用范围
    • 34
    • 28
    • 22
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to CCR8.
    纯化方法
    Purified
    免疫原
    Antibody raised against a synthetic peptide corresponding to amino acids 183 to 201 of the human CCR8. Peptide sequence is located in the second extracellular loop.
    亚型
    IgG
    Top Product
    Discover our top product CCR8 Primary Antibody
  • 应用备注
    Western Blot: 0.5 to 1 μg/mL. Detects an approximately 50 kDa band in human spleentissue lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline solution containing 0.02 % sodium azide as a preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at 2-8 °C.
  • 抗原
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    别名
    CDw198 / CCR8 (CCR8 产品)
    别名
    CC-CKR-8 antibody, CCR-8 antibody, CDw198 antibody, CKRL1 antibody, CMKBR8 antibody, CMKBRL2 antibody, CY6 antibody, GPRCY6 antibody, TER1 antibody, C-C antibody, C-C CKR-8 antibody, CKR-8 antibody, Cmkbr8 antibody, mCCR8 antibody, C-C motif chemokine receptor 8 antibody, chemokine (C-C motif) receptor 8 antibody, CCR8 antibody, Ccr8 antibody
    背景
    CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR11-4. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains5. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.Synonyms: C-C CKR-8, C-C chemokine receptor type 8, CC-CKR-8, CC-chemokine receptor CHEMR1, CCR-8, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, GPR-CY6, TER1
    基因ID
    1237
    NCBI登录号
    NP_005192
    UniProt
    P51685
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