电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

p53 抗体 (AA 371-380)

The 绵羊 多克隆 anti-p53 antibody is suitable to detect p53 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IP 和 IHC (fro).
产品编号 ABIN264905
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for p53 抗体 (AA 371-380) (ABIN264905)

抗原

See all p53 (TP53) 抗体
p53 (TP53) (Tumor Protein P53 (TP53))

适用

  • 1081
  • 341
  • 270
  • 140
  • 75
  • 74
  • 54
  • 37
  • 11
  • 10
  • 10
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 815
  • 294
  • 3
  • 2
  • 2
  • 2
绵羊

克隆类型

  • 605
  • 512
  • 1
多克隆

标记

  • 561
  • 57
  • 33
  • 23
  • 22
  • 22
  • 22
  • 22
  • 22
  • 21
  • 20
  • 16
  • 14
  • 14
  • 14
  • 14
  • 14
  • 14
  • 14
  • 14
  • 13
  • 13
  • 13
  • 13
  • 13
  • 13
  • 13
  • 12
  • 11
  • 11
  • 11
  • 11
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This p53 antibody is un-conjugated

应用范围

  • 835
  • 352
  • 297
  • 294
  • 272
  • 169
  • 150
  • 147
  • 131
  • 122
  • 64
  • 56
  • 25
  • 17
  • 12
  • 9
  • 8
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 48
    • 39
    • 39
    • 36
    • 34
    • 32
    • 31
    • 30
    • 27
    • 27
    • 27
    • 24
    • 20
    • 20
    • 20
    • 19
    • 19
    • 18
    • 17
    • 16
    • 16
    • 14
    • 13
    • 12
    • 12
    • 10
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    AA 371-380

    特异性

    This antibody reacts to GST p53.

    纯化方法

    Purified

    亚型

    IgG
  • 应用备注

    Western Blot: 1 - 10 μg/mL. Immunoprecipitation on formalin-fixed and paraffin embedded tissue.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    Phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    p53 (TP53) (Tumor Protein P53 (TP53))

    别名

    p53 (TP53)

    背景

    GST p53 fusion protein containing amino acids 1-393 of human p53was used as immunogen. p53 has a molecular weight of 53 kDa p53 is a transcription factor that can inhibit cell cycle progression or induce apoptosis in response to stress or DNA damage. Disruption of the p53 signalling pathway through various mechanisms is the most common alteration in human cancer occuring in over half of all tumors. The p53 protein is short lived and expressed at low levels in normal cells but accumulates and/or is activated in cells that have undergone genotoxic damage or oncogene activation. Many tumor derived and transformed cell lines express elevated levels of mutant p53 protein.Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53

    基因ID

    7157

    NCBI登录号

    NP_000537

    UniProt

    P04637

    途径

    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
You are here: