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Retinoblastoma 1 抗体 (AA 300-380)

The 小鼠 单克隆 anti-Retinoblastoma 1 antibody is suitable to detect Retinoblastoma 1 in samples from 人, 小鼠, 大鼠 和 小鸡. It has been validated for IP.
产品编号 ABIN264374
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Retinoblastoma 1 抗体 (AA 300-380) (ABIN264374)

抗原

See all Retinoblastoma 1 (RB1) 抗体
Retinoblastoma 1 (RB1)

适用

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人, 小鼠, 大鼠, 小鸡

宿主

  • 260
  • 34
小鼠

克隆类型

  • 213
  • 81
单克隆

标记

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This Retinoblastoma 1 antibody is un-conjugated

应用范围

  • 239
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  • 10
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Immunoprecipitation (IP)

克隆位点

C36
  • 抗原表位

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    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
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    • 1
    AA 300-380

    特异性

    Retinoblastoma binds and regulates E2F transcription factors.

    产品特性

    Synonyms: Retinoblastoma 1, Rb, p105-Rb, pRb, pp110, OSRC

    纯化方法

    From ascites.

    免疫原

    Recombinant protein corresponding to amino acids 300 to 380 of the humanretinoblastoma sequence.

    亚型

    IgG1
  • 应用备注

    Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.08 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.

    有效期

    12 months
  • 抗原

    Retinoblastoma 1 (RB1)

    别名

    Retinoblastoma-Associated Protein / RB1

    背景

    Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes.Synonyms: OSRC, Rb, Retinoblastoma 1, p105-Rb, pRb, pp110

    基因ID

    5925

    UniProt

    P06400

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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