Retinoblastoma 1 抗体 (AA 300-380)
Our Local Distributor
北京 101111
Quick Overview for Retinoblastoma 1 抗体 (AA 300-380) (ABIN264374)
抗原
See all Retinoblastoma 1 (RB1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 300-380
-
特异性
- Retinoblastoma binds and regulates E2F transcription factors.
-
产品特性
- Synonyms: Retinoblastoma 1, Rb, p105-Rb, pRb, pp110, OSRC
-
纯化方法
- From ascites.
-
免疫原
- Recombinant protein corresponding to amino acids 300 to 380 of the humanretinoblastoma sequence.
-
亚型
- IgG1
-
-
-
-
应用备注
-
Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.08 % Sodium Azide as preservative.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
-
Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
有效期
- 12 months
-
-
- Retinoblastoma 1 (RB1)
-
别名
- Retinoblastoma-Associated Protein / RB1
-
背景
- Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes.Synonyms: OSRC, Rb, Retinoblastoma 1, p105-Rb, pRb, pp110
-
基因ID
- 5925
-
UniProt
- P06400
-
途径
- Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
抗原
-