TNC 抗体
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- 抗原 See all TNC 抗体
- TNC (Tenascin C (TNC))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNC antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- A 265 kD protein. Tenascin C contains an extensive number of potential glycosylation sites, which may explain its migration at a higher molecular weight than predicted. Human tonsilar tissue can be used as a positive control in immunocytochemistry and immunohistochemistry.
- 纯化方法
- Purified
- 免疫原
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T2H5 is a mouse monoclonal IgG1 antibody derived by fusion of mouse myeloma cells with spleen cells from a BALB/c mouse immunized with full length native tenascin protein purified from a homogenate of a human mammary tumor specimen.
Type of Immunogen: Purified protein - 克隆位点
- T2H5
- 亚型
- IgG1
- Top Product
- Discover our top product TNC Primary Antibody
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- 应用备注
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Approved: ICC, IHC, IHC-Fr, IHC-P, IP, WB
Usage: Tenascin is a high molecular weight, multifunctional, extracellular matrix glycoprotein expressed in association with mesenchymal-epithelial interactions during development. It has been described under a variety of names, i. e. cytotactin, hexabrachion protein, J1, myotendinous antigen and glioma mesenchymal extracellular matrix. In undifferentiated tumors it is also detectable in the neovasculature and stroma. The tenascin molecule is a disulfide-linked hexamer. The expression of tenascin is associated with development and growth, both normal and pathological, whereas the distribution in normal adult tissue is restricted. For example, this extracellular matrix protein is implicated in guidance of migrating neurons as well as axons during neural development as well as neuronal regeneration. In in vitro studies it promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. The cellular ligands for tenascin include integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C, or in small aliquots at -20°C.
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- 抗原
- TNC (Tenascin C (TNC))
- 别名
- TNC / Tenascin C (TNC 产品)
- 别名
- tn antibody, 150-225 antibody, GMEM antibody, GP antibody, HXB antibody, JI antibody, TN antibody, TN-C antibody, AI528729 antibody, C130033P17Rik antibody, Hxb antibody, Ten antibody, cytotactin antibody, tenascin-C antibody, P230 antibody, tenc antibody, wu:fk04d02 antibody, tenascin C L homeolog antibody, tenascin C antibody, tnc.L antibody, TNC antibody, MCYG_00667 antibody, tnc antibody, Tnc antibody
- 背景
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Name/Gene ID: TNC
Family: Fibronectin
Synonyms: TNC, 150-225, Cytotactin, GP, Hexabrachion (tenascin), GMEM, GP 150-225, Miotendinous antigen, Myotendinous antigen, JI, Tenascin, Tenascin C, Neuronectin, Tenascin-C isoform 14/AD1/16, TN-C, Hexabrachion, HXB, Tenascin-C, TN - 基因ID
- 3371
- 途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
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