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TEK 抗体 (pTyr992)

TEK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2568495
发货至: 中国
  • 抗原 See all TEK 抗体
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    抗原表位
    • 19
    • 19
    • 16
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr992
    适用
    • 129
    • 66
    • 49
    • 22
    • 4
    • 3
    人, 小鼠
    宿主
    • 121
    • 17
    • 3
    • 2
    • 2
    克隆类型
    • 127
    • 18
    多克隆
    标记
    • 69
    • 9
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    This TEK antibody is un-conjugated
    应用范围
    • 74
    • 53
    • 40
    • 40
    • 31
    • 27
    • 13
    • 13
    • 12
    • 8
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The Antibody detects endogenous levels of TIE2 only when phosphorylated at Tyr992.
    纯化方法
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    免疫原
    TIE2 (phospho Tyr992) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 992 (E-V-Y (p)-V-K) derived from Human TIE2.
    亚型
    IgG
    Top Product
    Discover our top product TEK Primary Antibody
  • 应用备注
    Western Blot: 1:500~1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store antibody at -20°C for up to one year.
  • 抗原
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    别名
    TIE2 (TEK 产品)
    别名
    TEK antibody, DKFZp469E064 antibody, AA517024 antibody, Cd202b antibody, Hyk antibody, Tie2 antibody, tie-2 antibody, CD202B antibody, TIE-2 antibody, TIE2 antibody, VMCM antibody, VMCM1 antibody, Tie-2 antibody, tie2 antibody, TEK receptor tyrosine kinase antibody, angiopoietin-1 receptor antibody, TEK tyrosine kinase, endothelial antibody, TEK antibody, LOC100408334 antibody, tek antibody, Tek antibody
    背景
    The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
    分子量
    126 kDa
    基因ID
    7010
    NCBI登录号
    NP_000450
    UniProt
    Q02763
    途径
    RTK signaling, Growth Factor Binding
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