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SREBF1 抗体 (pSer439)

SREBF1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2568461
发货至: 中国
  • 抗原 See all SREBF1 抗体
    SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
    抗原表位
    • 12
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer439
    适用
    • 63
    • 26
    • 19
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 59
    • 8
    克隆类型
    • 58
    • 8
    多克隆
    标记
    • 42
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This SREBF1 antibody is un-conjugated
    应用范围
    • 46
    • 29
    • 13
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The antibody detects endogenous level of SREBP-1 only when phosphorylated at serine 439.
    纯化方法
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    免疫原
    SREBP-1 (phospho Ser439) antibody was raised against a peptide sequence around phosphorylation site of serine439 (Q-S-S (p)-P-L) derived from Human SREBP-1 .
    亚型
    IgG
    Top Product
    Discover our top product SREBF1 Primary Antibody
  • 应用备注
    Western Blot: 1:500~1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store antibody at -20°C for up to one year.
  • 抗原
    SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
    别名
    SREBP-1 (SREBF1 产品)
    别名
    SREBP-1c antibody, SREBP1 antibody, bHLHd1 antibody, ADD-1 antibody, ADD1 antibody, D630008H06 antibody, SREBP-1 antibody, SREBP-1a antibody, SREBP1c antibody, Srebp1 antibody, SCREBP1 antibody, SREBP-1C antibody, SREBF1 antibody, srebp1 antibody, sterol regulatory element binding transcription factor 1 antibody, sterol regulatory element binding transcription factor 1 L homeolog antibody, sterol regulatory element binding protein-1 antibody, Sterol regulatory element Binding Protein antibody, SREBF1 antibody, Srebf1 antibody, srebf1.L antibody, SREBP-1 antibody, srebf1 antibody, sbp-1 antibody
    背景
    Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway By similarity. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').
    分子量
    122 kDa
    基因ID
    6720
    NCBI登录号
    NP_001005291
    UniProt
    P36956
    途径
    AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
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