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GRIN1/NMDAR1 抗体 (AA 42-361) (Biotin)

GRIN1 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S308-48 Biotin
产品编号 ABIN2483590
发货至: 中国
  • 抗原 See all GRIN1/NMDAR1 (GRIN1) 抗体
    GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
    抗原表位
    • 34
    • 27
    • 20
    • 17
    • 15
    • 5
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    AA 42-361
    适用
    • 133
    • 125
    • 102
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 136
    • 30
    • 1
    • 1
    小鼠
    克隆类型
    • 129
    • 39
    单克隆
    标记
    • 73
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
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    • 3
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 2
    • 2
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    • 2
    This GRIN1/NMDAR1 antibody is conjugated to Biotin
    应用范围
    • 119
    • 56
    • 42
    • 41
    • 40
    • 26
    • 18
    • 18
    • 13
    • 10
    • 10
    • 3
    • 2
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Detects ~105 kDa.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Protein G Purified
    免疫原
    Fusion protein amino acids 42-361 (extracellular N-terminus) of rat NR1
    克隆位点
    S308-48
    亚型
    IgG1
    Top Product
    Discover our top product GRIN1 Primary Antibody
  • 应用备注
    • WB (1:1000)
    • IHC (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN2483590 was sufficient for detection of NR1 glutamate receptor in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
    别名
    GluN1 (GRIN1 产品)
    别名
    GluN1 antibody, MRD8 antibody, NMDA1 antibody, NMDAR1 antibody, NR1 antibody, nmda1 antibody, nmdar1 antibody, GB19253 antibody, GRIN1 antibody, NMD-R1 antibody, Z16 antibody, GluRdelta1 antibody, GluRzeta1 antibody, M100174 antibody, Nmdar antibody, Rgsc174 antibody, NMDAR1.1 antibody, zgc:152678 antibody, glutamate ionotropic receptor NMDA type subunit 1 antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 1 S homeolog antibody, NMDA receptor 1 antibody, G protein-regulated inducer of neurite outgrowth 1 antibody, glutamate receptor, ionotropic, NMDA1 (zeta 1) antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 1a antibody, GRIN1 antibody, grin1.S antibody, grin1 antibody, Grin1 antibody, Nmdar1 antibody, Gprin1 antibody, grin1a antibody
    背景
    The NMDA receptor (NMDAR), a glutamate receptor, is the predominant molecular device for controlling synaptic plasticity and memory function (1). The NMDA receptor forms a heterotetramer between two NR1 and two NR2 subunits (the subunits are also called glutamate-binding NMDA receptor subunits or GluN for short), two obligatory NR1 subunits and two regionally localized NR2 subunits. A related gene family of NR3 A and B subunits have an inhibitory effect on receptor activity. Multiple receptor isoforms with distinct brain distributions and functional properties arise by selective splicing of the NR1 transcripts and differential expression of the NR2 subunits.
    基因ID
    24408
    NCBI登录号
    NP_058706
    UniProt
    P35439
    途径
    Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
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