GRIN1/NMDAR1 产品
(Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
Categories
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
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Featured GRIN1/NMDAR1 Categories
GRIN1/NMDAR1 抗体
High quality antibodies with extensive validation data.
GRIN1/NMDAR1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
GRIN1/NMDAR1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GRIN1/NMDAR1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IF
Validations
- (5)
Cat. No.
ABIN185678
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (4)
Cat. No.
ABIN6141400
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6263664
Quantity
100 μL
Datasheet
Datasheet
Recommended GRIN1/NMDAR1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967062
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967061
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967060
Quantity
96 tests
Datasheet
Datasheet
Recommended GRIN1/NMDAR1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN6923002
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3084401
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3084402
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GRIN1/NMDAR1 Products
: "Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities." in: Disease models & mechanisms, Vol. 12, Issue 2, (2019) (PubMed).: "Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons." in: JCI insight, Vol. 5, (2019) (PubMed).
: "Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. ..." in: Nature medicine, Vol. 24, Issue 3, pp. 313-325, (2018) (PubMed).
: "2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor." in: Journal of cellular physiology, (2017) (PubMed).
: "Pharmacological inhibition of PTEN attenuates cognitive deficits caused by neonatal repeated exposures to isoflurane via inhibition of NR2B-mediated tau phosphorylation in rats." in: Neuropharmacology, Vol. 114, pp. 135-145, (2017) (PubMed).
: "Motor neuron degeneration following glycine-mediated excitotoxicity induces spastic paralysis after spinal cord ischemia/reperfusion injury in rabbit." in: American journal of translational research, Vol. 9, Issue 7, pp. 3411-3421, (2017) (PubMed).
: "Spontaneous Glutamatergic Synaptic Activity Regulates Constitutive COX-2 Expression in Neurons: OPPOSING ROLES FOR THE TRANSCRIPTION FACTORS CREB (cAMP RESPONSE ELEMENT BINDING) PROTEIN AND Sp1 ..." in: The Journal of biological chemistry, Vol. 291, Issue 53, pp. 27279-27288, (2016) (PubMed).
: "Mechanisms responsible for the effect of median nerve electrical stimulation on traumatic brain injury-induced coma: orexin-A-mediated N-methyl-D-aspartate receptor subunit NR1 upregulation." in: Neural regeneration research, Vol. 11, Issue 6, pp. 951-6, (2016) (PubMed).
: "Altered GluN2B NMDA receptor function and synaptic plasticity during early pathology in the PS2APP mouse model of Alzheimer's disease." in: Neurobiology of disease, Vol. 74, pp. 254-62, (2015) (PubMed).
: "Conantokin-G attenuates detrimental effects of NMDAR hyperactivity in an ischemic rat model of stroke." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122840, (2015) (PubMed).
Synonyms and alternative names related to GRIN1/NMDAR1
glutamate ionotropic receptor NMDA type subunit 1 (GRIN1), glutamate receptor, ionotropic, N-methyl D-aspartate 1 S homeolog (grin1.S), glutamate ionotropic receptor NMDA type subunit 1 (grin1), glutamate ionotropic receptor NMDA type subunit 1 (Grin1), NMDA receptor 1 (Nmdar1), G protein-regulated inducer of neurite outgrowth 1 (Gprin1), glutamate receptor, ionotropic, NMDA1 (zeta 1) (Grin1), glutamate receptor, ionotropic, N-methyl D-aspartate 1a (grin1a), GB19253, GluN1, GluRdelta1, GluRzeta1, GRIN1, M100174, MRD8, NMD-R1, NMDA1, nmda1, Nmdar, NMDAR1, nmdar1, NMDAR1.1, NR1, Rgsc174, Z16, zgc:152678Protein level used designations for GRIN1/NMDAR1
- N-methyl-D-aspartate receptor channel, subunit zeta-1
- N-methyl-D-aspartate receptor subunit NR1
- NMD-R1
- glutamate [NMDA] receptor subunit zeta 1
- glutamate [NMDA] receptor subunit zeta-1
- glutamate receptor ionotropic, NMDA 1
- N-methyl-D-aspartate receptor
- NMDA glutamate receptor
- glutamate receptor, ionotropic, N-methyl D-aspartate 1
- N-methyl-D-aspartate glutamate receptor
- NMDA R1 receptor C1 cassette
- neurotransmitter receptor
- NMDA-type glutamate receptor 1
- NMDA-type glutamate receptor subunit 1
- N-methyl-D-aspartate receptor 1
- Glutamate [NMDA] receptor subunit zeta-1
- glutamate receptor subunit zeta 1
- N-methyl-D-aspartate receptor type 1
- NMDA receptor glycine-binding subunit NR1.1
- glutamate receptor, ionotropic, N-methyl D-aspartate 1a
- round spermatid basic protein 1
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