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GRK4 产品

(G Protein-Coupled Receptor Kinase 4 (GRK4))

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This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. [provided by RefSeq, Jul 2008].

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Featured GRK4 Categories

GRK4 抗体

High quality antibodies with extensive validation data.

GRK4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GRK4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7153293
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN561104
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN5013580
Quantity 100 μL
Datasheet Datasheet

Recommended GRK4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570588
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355764
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3081164
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GRK4 Products

Villar, Jones, Armando, Palmes-Saloma, Yu, Pascua, Keever, Arnaldo, Wang, Luo, Felder, Jose: "G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor." in: The Journal of biological chemistry, Vol. 284, Issue 32, pp. 21425-34, (2009) (PubMed).

Perroy, Adam, Qanbar, Chénier, Bouvier: "Phosphorylation-independent desensitization of GABA(B) receptor by GRK4." in: The EMBO journal, Vol. 22, Issue 15, pp. 3816-24, (2003) (PubMed).

Watanabe, Xu, Bengra, Jose, Felder: "Desensitization of human renal D1 dopamine receptors by G protein-coupled receptor kinase 4." in: Kidney international, Vol. 62, Issue 3, pp. 790-8, (2002) (PubMed).

Sallese, Mariggiò, Collodel, Moretti, Piomboni, Baccetti, De Blasi: "G protein-coupled receptor kinase GRK4. Molecular analysis of the four isoforms and ultrastructural localization in spermatozoa and germinal cells." in: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10188-95, (1997) (PubMed).

Premont, Macrae, Stoffel, Chung, Pitcher, Ambrose, Inglese, MacDonald, Lefkowitz: "Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants." in: The Journal of biological chemistry, Vol. 271, Issue 11, pp. 6403-10, (1996) (PubMed).

Sallese, Lombardi, De Blasi: "Two isoforms of G protein-coupled receptor kinase 4 identified by molecular cloning." in: Biochemical and biophysical research communications, Vol. 199, Issue 2, pp. 848-54, (1994) (PubMed).

Synonyms and alternative names related to GRK4

G protein-coupled receptor kinase 4 (GRK4), G protein-coupled receptor kinase 4 (Grk4), AMP-activated protein kinase alpha subunit (AMPKalpha), G protein-coupled receptor kinase 4 L homeolog (grk4.L), G protein-coupled receptor kinase 4 S homeolog (grk4.S), G protein-coupled receptor kinase 4 (grk4), G protein-coupled receptor kinase 4 (LOC100540688), A830025H08Rik, AMPK, ampk, AMPKalpha, ampkalpha, CG3051, dAMPKa, dAMPKalpha, DmAMPK alpha, Dmel\\CG3051, EG:132E8.2, FBgn0023169, Gprk-4, GPRK2L, Gprk2l, gprk2l, GPRK4, Gprk4, gprk4, gprk4-a, gprk4-b, GRK, grk4, GRK4, GRK4a, grk4a, IT11, it11, snf1a, zgc:153020

Protein level used designations for GRK4

  • ITI1
  • G protein-coupled receptor kinase 2, groucho gene related
  • g protein-coupled receptor kinase GRK4
  • 5'monophosphate-activated kinase
  • AMP-activated kinase
  • AMP-activated protein kinase
  • AMP-dependent kinase
  • CG3051-PA
  • CG3051-PB
  • CG3051-PC
  • G protein-coupled receptor kinase 4
  • SNF/AMP-activated protein S/T kinase gamma subunit
  • SNF1A-PA
  • SNF1A-PB
  • SNF1A-PC
  • adenosine monophosphate-activated protein kinase
  • GRK5
  • G-protein-coupled receptor kinase 2-like
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