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GRM8 产品

(Glutamate Receptor, Metabotropic 8 (GRM8))
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Featured GRM8 Categories

GRM8 抗体

High quality antibodies with extensive validation data.

GRM8 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GRM8 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GRM8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (5)
Cat. No. ABIN5611162
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7181343
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Chicken, Dog, Hamster, Horse, Human, Monkey, Mouse, Rabbit, Rat, Sheep
Application IHC, IHC (p), ICC
Validations
  • (3)
Cat. No. ABIN1048944
Quantity 50 μg
Datasheet Datasheet

Recommended GRM8 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381317
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1771763
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774211
Quantity 96 tests
Datasheet Datasheet

Recommended GRM8 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355789
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3081266
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134130
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GRM8 Products

Downey, Lozza, Petrò, Diodato, Foglia, Bottazzoli, Brusa, Asquini, Reggiani, Grilli: "Ecdysone-based system for controlled inducible expression of metabotropic glutamate receptor subtypes 2, 5, and 8." in: Journal of biomolecular screening, Vol. 10, Issue 8, pp. 841-8, (2006) (PubMed).

Synonyms and alternative names related to GRM8

glutamate metabotropic receptor 8 (GRM8), metabotropic glutamate receptor 8 (MGLUR8), metabotropic glutamate receptor 8 (LOAG_14062), glutamate receptor, metabotropic 8 (Grm8), glutamate metabotropic receptor 8 (Grm8), A230002O04, GLUR8, Glur8, GPRC1H, Gprc1h, GRM8, mGlu8, mGlur, mGluR8, MGLUR8, Mglur8, mGluR8b

Protein level used designations for GRM8

  • metabotropic glutamate receptor 8
  • metabotropic type glutamate receptor 8
  • glutamate receptor, metabotropic 8
  • G protein coupled receptor, family C, group 1, member H
  • G protein-coupled receptor, family C, group 1, member H
  • G protein-coupled receptor family C group 1 member H
  • metabotropic glutamate receptor subtype 8b
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