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GRM8 抗体 (AA 440-583)

GRM8 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 4C1C1 unconjugated
产品编号 ABIN5611162
发货至: 中国
  • 抗原 See all GRM8 抗体
    GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
    抗原表位
    • 12
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 440-583
    适用
    • 36
    • 24
    • 15
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 34
    • 2
    小鼠
    克隆类型
    • 35
    • 1
    单克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRM8 antibody is un-conjugated
    应用范围
    • 23
    • 17
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human GRM8 (AA: extra 440-583) expressed in E. coli.
    克隆位点
    4C1C1
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
    别名
    GRM8 (GRM8 产品)
    别名
    mGluR8 antibody, GRM8 antibody, MGLUR8 antibody, GLUR8 antibody, GPRC1H antibody, mGlu8 antibody, A230002O04 antibody, Gprc1h antibody, Glur8 antibody, Mglur8 antibody, mGluR8b antibody, mGlur antibody, glutamate metabotropic receptor 8 antibody, metabotropic glutamate receptor 8 antibody, glutamate receptor, metabotropic 8 antibody, GRM8 antibody, MGLUR8 antibody, LOAG_14062 antibody, Grm8 antibody
    背景

    Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Aliases: GLUR8, mGlu8, GPRC1H, MGLUR8

    分子量
    101.7 kDa
    基因ID
    2918
    HGNC
    2918
    途径
    cAMP Metabolic Process, Synaptic Membrane
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