GRM8 抗体 (AA 810-890)
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Quick Overview for GRM8 抗体 (AA 810-890) (ABIN7221376)
抗原
See all GRM8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 810-890
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原理
- Rabbit Anti-mGluR-8 Polyclonal Antibody
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特异性
- MGluR-8 Polyclonal Antibody detects endogenous levels of mGluR-8 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human mGluR-8 at AA range: 810-890
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亚型
- IgG
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anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 440-583) antibody
GRM8 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4C1C1 unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (N-Term) antibodyGRM8 适用: 人, 小鼠, 大鼠, 猴, 兔, Bat, 马, 小鸡, 犬, Hamster, 绵羊 IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) antibodyGRM8 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 486-575) antibodyGRM8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A7 unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (C-Term) antibodyGRM8 适用: 人, 小鼠, 大鼠, 猴, Bat, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 486-575) antibodyGRM8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (Extracellular Domain), (N-Term) antibodyGRM8 适用: 人 IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 841-890) antibodyGRM8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 365-377), (Extracellular) antibodyGRM8 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
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别名
- mGluR-8
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背景
- GRM8, GPRC1H, MGLUR8, Metabotropic glutamate receptor 8, mGluR8L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for GRM8.
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分子量
- 100kD
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基因ID
- 2918
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UniProt
- O00222
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途径
- cAMP Metabolic Process, Synaptic Membrane
抗原
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