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ORAI3 抗体 (N-Term)

ORAI3 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2470539
发货至: 中国
  • 抗原 See all ORAI3 抗体
    ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
    抗原表位
    • 13
    • 10
    • 9
    • 1
    • 1
    • 1
    N-Term
    适用
    • 26
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 23
    • 3
    克隆类型
    • 23
    • 3
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This ORAI3 antibody is un-conjugated
    应用范围
    • 26
    • 17
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity Chromatography
    免疫原
    ORAI3 antibody was raised against a peptide near the N-Terminus of ORAI3 (Human).
    Top Product
    Discover our top product ORAI3 Primary Antibody
  • 应用备注
    ORAI3 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, immunofluorescence starting at 10 μg/mL, and immunoprecipitation.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies avoid freeze/thaw cycles. Store undiluted.
    储存条件
    4 °C/-20 °C
    储存方法
    Store ORAI3 antibody at 4 °C or -20 °C.
  • 抗原
    ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
    别名
    ORAI3 (ORAI3 产品)
    别名
    ORAI3 antibody, TMEM142C antibody, 9930124N15 antibody, BC061259 antibody, Tmem142c antibody, RGD1306538 antibody, ORAI calcium release-activated calcium modulator 3 antibody, ORAI3 antibody, Orai3 antibody
    背景
    Recognizes human ORAI3, also known as Transmembrane protein 142C (TMEM142C), a 31.5 kDa multi-pass membrane protein belonging to the ORAI family. Antigen stimulation of immune cells triggers Ca2+ entry through Ca2+ release-activated Ca2+ (CRAC) channels. CRAC channels are the main pathway for Ca2+ influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT. ORAI3 is one of two mammalian homologs of ORAI1, a four- transmembrane spanning protein that is an essential component of CRAC channels. ORAI3, along with ORAI1 and ORAI2, functions as a Ca2+ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca2+ sensor. Studies indicate that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Is not expected to cross react with either ORAI1 or ORAI2.
    基因ID
    93129
    UniProt
    Q9BRQ5
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