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ORAI3 抗体 (C-Term)

ORAI3 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990753
发货至: 中国
  • 抗原 See all ORAI3 抗体
    ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
    抗原表位
    • 13
    • 10
    • 8
    • 1
    • 1
    AA 200-250, C-Term
    适用
    • 25
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 22
    • 3
    克隆类型
    • 22
    • 3
    多克隆
    标记
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    This ORAI3 antibody is un-conjugated
    应用范围
    • 25
    • 16
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    ORAI3 antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2.
    纯化方法
    ORAI3 Antibody is affinity chromatography purified via peptide column.
    免疫原
    ORAI3 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human ORAI3. The immunogen is located within amino acids 200 - 250 of ORAI3.
    亚型
    IgG
    Top Product
    Discover our top product ORAI3 Primary Antibody
  • 应用备注
    ORAI3 antibody can be used for detection of ORAI3 by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    ORAI3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    ORAI3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
    别名
    ORAI3 (ORAI3 产品)
    别名
    ORAI3 antibody, TMEM142C antibody, 9930124N15 antibody, BC061259 antibody, Tmem142c antibody, RGD1306538 antibody, ORAI calcium release-activated calcium modulator 3 antibody, ORAI3 antibody, Orai3 antibody
    背景
    ORAI3 Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extracellular Ca++, indicating that each have similar affinities for Ca++ within the selectivity filter.
    分子量
    Predicted: 32 kDa

    Observed: 34 kDa
    基因ID
    93129
    UniProt
    Q9BRQ5
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