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TACI 抗体 (AA 116-132)

TNFRSF13B 适用: 人, 小鼠 WB, FACS, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2470171
发货至: 中国
  • 抗原 See all TACI (TNFRSF13B) 抗体
    TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
    抗原表位
    • 16
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 116-132
    适用
    • 31
    • 26
    • 7
    • 2
    • 2
    • 2
    • 2
    人, 小鼠
    宿主
    • 32
    • 10
    • 10
    • 3
    克隆类型
    • 34
    • 21
    多克隆
    标记
    • 30
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TACI antibody is un-conjugated
    应用范围
    • 40
    • 18
    • 16
    • 14
    • 14
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)
    纯化方法
    Protein G Column
    免疫原
    TNFRSF13B antibody was raised against amino acids 116 - 132 of TNFRSF13B (Human).
    亚型
    IgG
    Top Product
    Discover our top product TNFRSF13B Primary Antibody
  • 应用备注
    TNFRSF13B antibody can be used in Western Blot starting at 1:1000, immunohistochemistry starting at 5 μg/mL, immunohistochemistry -Pfa starting at 1 μg/mL, and flow cytometry.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.05 % sodium azide and 0.2 % gelatin.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies avoid freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    TNFRSF13B antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.
  • 抗原
    TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
    别名
    TNFRSF13B (TNFRSF13B 产品)
    别名
    CD267 antibody, CVID antibody, CVID2 antibody, RYZN antibody, TACI antibody, TNFRSF14B antibody, TNFRSF13B antibody, 1200009E08Rik antibody, Taci antibody, TNF receptor superfamily member 13B antibody, tumor necrosis factor receptor superfamily, member 13b antibody, TNFRSF13B antibody, Tnfrsf13b antibody
    背景
    Simultaneously four different laboratories identified a a new member of the tumor necrosis factor (TNF) family. This has been named as TALL-1 , THANK (TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase , BAFF (for B cell activating factor belonging to the TNF family) and BlyS (B lymphocyte stimulator). Membrane-bound BAFF is processed and secreted through the action of a protease whose specificity matches that of the furin family of proprotein convertases. The receptor for BlyS/BAFF appears to be expressed predominantly on B cells and activated T cells. Recently two orphan receptors TACI and BCMA (,8) have been shown to be receptors for BlyS/BAFF (6-9). TACI is expressed on B cells and signals through CAML, activating the transcription factors NF-AT, NF-κ,B, and AP-1. TACI is one of three know receptors for BLys. Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-κ,B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
    基因ID
    23495
    UniProt
    O14836
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