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- 抗原 See all ADRA2B 抗体
- ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
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抗原表位
- AA 200-299
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适用
- 人
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宿主
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小鸡
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克隆类型
- 多克隆
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标记
- This ADRA2B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Immunoaffinity Purified
- Top Product
- Discover our top product ADRA2B Primary Antibody
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anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 343-369) antibody
ADRA2B 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22486 unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 349-378) antibodyADRA2B 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (Intracellular) antibodyADRA2B 适用: 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 5G10 unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 343-369) antibodyADRA2B 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) antibodyADRA2B 适用: 大鼠, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (AA 1-100) antibodyADRA2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-2B-, Receptor (ADRA2B) (2nd Extracellular Loop), (AA 160-174), (Cys169) antibodyADRA2B 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- alpha-2B adrenergic receptor antibody can be used for the detection of alpha-2B adrenergic receptor by Western Blot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate-Buffered Saline. No preservatives added.
- 储存液
- Without preservative
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- ADRA2B antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- 抗原
- ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
- 别名
- ADRA2B (ADRA2B 产品)
- 别名
- ADRA2L1 antibody, ADRA2RL1 antibody, ADRARL1 antibody, ALPHA2BAR antibody, alpha-2BAR antibody, Adra-2b antibody, [a]2B antibody, alpha2-C2 antibody, alpha2B antibody, ADRA2B antibody, zgc:194747 antibody, Adra2b antibody, adrenoceptor alpha 2B antibody, adrenergic receptor, alpha 2b antibody, adrenergic, alpha-2B-, receptor antibody, adrenoceptor alpha 2C antibody, ADRA2B antibody, Adra2b antibody, ADRA2C antibody, adra2b antibody
- 背景
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FUNCTION: alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
SUMMARY: alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. This protein is the alpha2B subtype, which was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization, this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. This protein contains no introns in either its coding or untranslated sequences. - 分子量
- 50 kDa (calculated)
- 基因ID
- 151
- NCBI登录号
- NP_000673
- UniProt
- P18089
- 途径
- EGFR Signaling Pathway, cAMP Metabolic Process
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