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ADRA2B 抗体 (AA 349-378)

ADRA2B 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN453503
发货至: 中国
  • 抗原 See all ADRA2B 抗体
    ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
    抗原表位
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 349-378
    适用
    • 22
    • 6
    • 4
    宿主
    • 22
    • 3
    • 1
    克隆类型
    • 23
    • 3
    多克隆
    标记
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADRA2B antibody is un-conjugated
    应用范围
    • 17
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Alpha-2B adrenergic receptor.
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 349~378 amino acids from the Center region of Human ADRA2B. Genename: ADRA2B
    Top Product
    Discover our top product ADRA2B Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
    别名
    alpha-2B Adrenergic Receptor (ADRA2B 产品)
    别名
    ADRA2L1 antibody, ADRA2RL1 antibody, ADRARL1 antibody, ALPHA2BAR antibody, alpha-2BAR antibody, Adra-2b antibody, [a]2B antibody, alpha2-C2 antibody, alpha2B antibody, ADRA2B antibody, zgc:194747 antibody, Adra2b antibody, adrenoceptor alpha 2B antibody, adrenergic receptor, alpha 2b antibody, adrenergic, alpha-2B-, receptor antibody, adrenoceptor alpha 2C antibody, ADRA2B antibody, Adra2b antibody, ADRA2C antibody, adra2b antibody
    背景
    Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha 2B adrenergic receptor subtype was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization, this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. Alpha 2B adrenergic receptor gene contains no introns in either its coding or untranslated sequences.Synonyms: ADRA2B, ADRA2L1, ADRA2RL1, Alpha-2B adrenoceptor, Alpha-2B adrenoreceptor
    基因ID
    151
    NCBI登录号
    NP_000673
    UniProt
    P18089
    途径
    EGFR Signaling Pathway, cAMP Metabolic Process
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