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IL-10 抗体

IL10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C12C12 unconjugated
产品编号 ABIN2464113
发货至: 中国
  • 抗原 See all IL-10 (IL10) 抗体
    IL-10 (IL10) (Interleukin 10 (IL10))
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    小鼠
    克隆类型
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    单克隆
    标记
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    This IL-10 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by protein A affinity chromatography.
    免疫原
    Ni-NTA purified recombinant human IL-10 expressed in E. Coli strain BL21 (DE3).
    克隆位点
    3C12C12
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IL10 Primary Antibody
  • 应用备注
    Western Blot:1:500 - 1,000
    ELISA:Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 缓冲液
    Purified antibody in PBS containing 0.03 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    储存条件
    -20 °C
    储存方法
    to IL-10 monoclonal antibody can be stored at -20 °C, stable for one year.
  • 抗原
    IL-10 (IL10) (Interleukin 10 (IL10))
    别名
    IL-10 (IL10 产品)
    别名
    CSIF antibody, GVHDS antibody, IL-10 antibody, IL10A antibody, TGIF antibody, Il-10 antibody, IL10X antibody, interleukin 10 antibody, IL10 antibody, Il10 antibody
    背景
    Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down- regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
    基因ID
    3586
    UniProt
    P22301
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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