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MME 抗体

MME 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2A1H5E1 unconjugated
产品编号 ABIN2464027
发货至: 中国
  • 抗原 See all MME 抗体
    MME (Membrane Metallo-Endopeptidase (MME))
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    小鼠
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    单克隆
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    This MME antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), ELISA
    纯化方法
    Antibody is purified by protein G affinity chromatography.
    免疫原
    Ni-NTA purified recombinant human CD-10 expressed in E. Coli strain BL21 (DE3).
    克隆位点
    2A1H5E1
    亚型
    IgG2b
    Top Product
    Discover our top product MME Primary Antibody
  • 应用备注
    IHC(P):Dilution 1:100 - 1:200
    IHC(F):Dilution 1:200 - 1:400
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 缓冲液
    Purified antibody in PBS containing 0.03 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    储存条件
    -20 °C
    储存方法
    CD10 monoclonal antibody can be stored at -20 °C, stable for one year.
  • 抗原
    MME (Membrane Metallo-Endopeptidase (MME))
    别名
    CD10 (MME 产品)
    别名
    CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody
    物质类
    Chemical
    背景
    CD10 is a 100 kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
    基因ID
    4311
    UniProt
    P08473
    途径
    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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