电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

NUP98 抗体

NUP98 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2463586
发货至: 中国
  • 抗原 See all NUP98 抗体
    NUP98 (Nucleoporin 98kDa (NUP98))
    适用
    • 45
    • 16
    • 12
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 34
    • 11
    • 1
    克隆类型
    • 33
    • 13
    多克隆
    标记
    • 36
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUP98 antibody is un-conjugated
    应用范围
    • 33
    • 15
    • 12
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NUP98.
    Top Product
    Discover our top product NUP98 Primary Antibody
  • 应用备注
    NUP98 antibody can be used for detection of NUP98 by ELISA at 1:62500. NUP98 antibody can be used for detection of NUP98 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store NUP98 antibody at -20 °C.
  • 抗原
    NUP98 (Nucleoporin 98kDa (NUP98))
    别名
    NUP98 (NUP98 产品)
    别名
    CG10198 antibody, CG10201 antibody, Dmel\\CG10198 antibody, Nup 96 antibody, Nup 98 antibody, Nup-98 antibody, Nup96 antibody, Nup98 antibody, Nup98-Nup96 antibody, Nup98/96 antibody, l(3)95BCd antibody, nup145 antibody, nup98-96 antibody, GB12688 antibody, NUP98 antibody, 4732457F17 antibody, AI849286 antibody, im:7151238 antibody, zgc:113968 antibody, zgc:63593 antibody, ADIR2 antibody, NUP196 antibody, NUP96 antibody, Nucleoporin 98-96kD antibody, nuclear pore complex protein Nup98-Nup96 antibody, nucleoporin 98 antibody, nucleoporin 98kDa antibody, nucleoporin 98 L homeolog antibody, Nup98-96 antibody, LOC408335 antibody, NUP98 antibody, LOC587580 antibody, Nup98 antibody, nup98 antibody, nup98.L antibody
    背景
    The nuclear pore complex (NPC) is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kD nucleoporin is localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kD nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kD nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kD precursor protein. This cleavage results in the 98 kD nucleoporin as well as a 96 kD nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kD nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.
    分子量
    98 kDa
    基因ID
    4928
    NCBI登录号
    NP_005378
    UniProt
    A8KA17
    途径
    Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
You are here:
客服