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NUP98 抗体 (FGxxN Motif, N-Term)

NUP98 适用: 人, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena WB, IF 宿主: 小鼠 Monoclonal 13C2 unconjugated
产品编号 ABIN2452065
发货至: 中国
  • 抗原 See all NUP98 抗体
    NUP98 (Nucleoporin 98kDa (NUP98))
    抗原表位
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    FGxxN Motif, N-Term
    适用
    • 47
    • 16
    • 12
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena
    宿主
    • 36
    • 10
    • 2
    小鼠
    克隆类型
    • 34
    • 14
    单克隆
    标记
    • 38
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUP98 antibody is un-conjugated
    应用范围
    • 35
    • 16
    • 12
    • 11
    • 7
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应 (详细)
    Not tested in other species
    纯化方法
    Purified
    过滤
    Sterile filtered
    免疫原
    Synthetic peptides containing conserved N-terminal sequence, GLFG, of Nup98 protein of Tetrahymena thermophila.
    克隆位点
    13C2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product NUP98 Primary Antibody
  • 应用备注
    1) Most suitable for Western blotting,(Human,S. cerevisiae,S. pombe,Tetrahymena.)
    2) Immunofluorescence staining / Immunocytochemistry for S. cerevisiae,S. pombe and T. etrahymena.
    Not suitable for IF in human
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, 50 % glycerol. Azide- and carrier protein-free.
    储存液
    Azide free
    储存条件
    -20 °C
    储存方法
    Upon arrival centrifuge briefly and store at -20 C.
  • Iwamoto, Asakawa, Ohtsuki, Osakada, Koujin, Hiraoka, Haraguchi: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).

    Iwamoto, Asakawa, Hiraoka, Haraguchi: "Nucleoporin Nup98: a gatekeeper in the eukaryotic kingdoms." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 15, Issue 7, pp. 661-9, (2010) (PubMed).

  • 抗原
    NUP98 (Nucleoporin 98kDa (NUP98))
    别名
    Nup98 (NUP98 产品)
    别名
    CG10198 antibody, CG10201 antibody, Dmel\\CG10198 antibody, Nup 96 antibody, Nup 98 antibody, Nup-98 antibody, Nup96 antibody, Nup98 antibody, Nup98-Nup96 antibody, Nup98/96 antibody, l(3)95BCd antibody, nup145 antibody, nup98-96 antibody, GB12688 antibody, NUP98 antibody, 4732457F17 antibody, AI849286 antibody, im:7151238 antibody, zgc:113968 antibody, zgc:63593 antibody, ADIR2 antibody, NUP196 antibody, NUP96 antibody, Nucleoporin 98-96kD antibody, nuclear pore complex protein Nup98-Nup96 antibody, nucleoporin 98 antibody, nucleoporin 98kDa antibody, nucleoporin 98 L homeolog antibody, Nup98-96 antibody, LOC408335 antibody, NUP98 antibody, LOC587580 antibody, Nup98 antibody, nup98 antibody, nup98.L antibody
    背景
    Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC), which is a large protein assembly embedded in the nuclear envelope and highly conserved in eukaryotes. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 also plays a specific role in the RNA export. In addition, Nup98 plays roles in several important biological events such as gene expression, mitotic checkpoint, and pathogenesis Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation. In ciliates, a unicellular organism having two functionally distinct nuclei, GLFG-Nup98 is present in one of the nuclei and a distinct Nup98 ortholog is present in the other nucleus, and these different Nup98s participate in a nucleus-selective transport mechanism.
    UniProt
    P52948
    途径
    Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
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